Chronic Sleep Disruptions can lead to Alzheimers:

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One in three Americans doesn’t get enough sleep, and 45% of the world’s population doesn’t, either. The US Centers for Disease Control and Prevention calls that a “public health problem,” because disrupted sleep is associated with a higher risk of conditions including diabetes, stroke and cardiovascular disease.

It may not be long before we can add Alzheimer’s and other types of dementia to that list.
It’s well known that people with Alzheimer’s suffer sleep issues. Insomnia, nighttime wandering and daytime sleepiness are common for them, as well as other cognitive disorders such as Lewy body dementia and frontal lobe dementia.
But could poor sleep earlier in life actually cause dementia?

Sleep and dementia

A growing body of research in both mice and humans shows that disturbed sleep leads to higher levels of soluble beta-amyloid, the protein that folds and forms the sticky plaques that kill brain cells and bog down information processing. Depositing amyloid in brain tissue is the first known preclinical stage of Alzheimer’s and happens well before any obvious symptoms of dementia begin.